Why do some of us age gracefully and others don’t? How do our bodies and minds experience aging at the cellular and molecular level? Why do we even age to begin with? And maybe most importantly, can we do anything about it?

Join host Gordon Lithgow at the Buck Institute in California as he speaks with some of the brightest scientific stars on the planet to search for – and actually find answers to – these questions and many more.

Listen on your favorite podcast app:

 

We’re not getting any younger…yet is made possible by a generous grant from the Navigage Foundation. Navigage enhances the lives of older people through the support of housing, health education and human services.

Gordon Lithgow

A native of Scotland, Dr. Lithgow received his PhD from the University of Glasgow and obtained further training at Ciba Geigy AG in Basel, Switzerland, and at the University of Colorado. He established his lab studying the biology of aging at the University of Manchester, England, before moving it to the Buck Institute in 2000.

Dr. Lithgow has been recognized for his research with a Glenn Award for Research in Biological Mechanisms of Aging, a senior scholarship from the Ellison Medical Foundation, and the Tenovus Award for Biomedical Research. He has served on many national advisory panels in both the UK and the US, including the National Institute on Aging’s Board of Scientific Counselors, and has served as the chair of biological sciences at the Gerontology Society of America. He has partnered with biotechnology companies in sponsored research and has strong collaborations in preclinical research on diseases such as osteoporosis and Parkinson’s disease.

#08 .
Scientific Wellness and AI at the Forefront
What do we really want from our healthcare system, and how can AI help us get it sooner? In our…
Listen ›
#07 .
Resilience as Medicine
Few people have as much experience with patient care and long-term research as the celebrated geriatrician and epidemiologist Luigi Ferrucci.…
Listen ›
#06 .
From Potential to Practice
The movement to integrate longevity treatments into clinical care is making strides. How can we ensure they are evidence-based, accessible,…
Listen ›
#05 .
Measuring the Pace of Aging
Our chronological age doesn’t tell us much about how well our bodies are aging, but scientists have developed many ways…
Listen ›
#04 .
Finding Targets for Aging Interventions
Of all the biochemical changes that occur with aging, what really matters? How can we use the incredible amount of…
Listen ›
#03 .
Fasting for Health and Longevity
What is the relationship between diet, chronic disease, and aging? Can we delay or reverse the effects of aging at…
Listen ›
#02 .
The Age of Circadian Disruption
Our modern world is full of potential disruptions to sleep. But as we learn more about circadian rhythm, we find…
Listen ›
#01 .
The Purpose and Promise of Longer Lives
What role does the immune system play in aging? How do senescent cells evade it and promote inflammation? And what…
Listen ›
#08 .
Immunity and Beyond
What role does the immune system play in aging? How do senescent cells evade it and promote inflammation? And what…
Listen ›
#07 .
Exploring the Wild World Within
How do different cells in our bodies age differently? What exactly happens when a neuron takes out its trash? In…
Listen ›
#06 .
The Secrets of Centenarians
Is aging truly inevitable? Can we study the genetics of long-lived people to learn how to delay or reverse aging?…
Listen ›
#05 .
The Nature of Aging
Aging appears to progress similarly across species, from worms and flies to mice and humans, and involves pathways related to…
Listen ›
#04 .
Training to Age Better
What is the relationship between stress, metabolism, and aging? How can we use “good” stress to enhance our ability to…
Listen ›
#03 .
Understanding Senescence
Dr. Campisi has been at the forefront of studying cellular senescence for decades, revealing the mysteries of these not-exactly-dead cells…
Listen ›
#02 .
An Information Theory of Aging
Is life essentially an information process driven by biochemical interactions? If so, can we simply correct any errors in that…
Listen ›
#01 .
Why do we age?
When we think of aging, we typically think of human aging, but the biological processes that cause cellular damage are…
Listen ›
#00 .
Trailer
Hi, I’m Gordon Lithgow. I’m a scientist who is looking at ways we can make getting older- better! This doesn't…
Listen ›

Support the Buck

We rely on donations to support the science that we believe will add years to people's lifespan and decades to their healthspan.