OUR MISSION
Our mission is to end the threat of age-related disease for this and future generations
We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that, we’re seeking a more comprehensive understanding of the biology of aging itself.
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Advancing the frontiers
of aging research
Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.
Featured News
News
Longevity-linked APOE2 gene variant helps neurons repair DNA and resist aging
Research from the Buck Institute reveals that the protective APOE2 variant, already associated with exceptional longevity and reduced Alzheimer's risk, keeps human brain cells genomically stable and resistant to cellular senescence
News
The Buck Institute Welcomes Renowned Cell Biologist Dr. Peter Walter to Faculty
Pioneering scientist whose discoveries transformed understanding of cellular health and disease joins Buck faculty
News
APOE4, the Alzheimer’s risk gene, silently undermines bone quality in women
Buck Institute researchers discover a surprising connection between a major risk factor for Alzheimer’s and bone quality deficits in female mice, pointing to osteocytes as a potential midlife early warning signal for both osteoporosis and Alzheimer’s
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