David G. Nicholls, PhD, Professor
Mitochondrial function and the life and death of cells
David Nicholls has researched mitochondrial function for 45 years and has more than 280 publications. He is perhaps best known as the author (now with Stuart Ferguson) of the standard textbook ‘Bioenergetics’, for his discovery of the original uncoupling protein, UCP1, for work on mitochondrial calcium transport and isolated nerve terminals and most recently for his research into mitochondrial dysfunction in nerve cells.
He established the Bioenergetics laboratory at the Buck in 2000 before handing it over to Martin Brand in 2008. He retains a part-time position in the Institute and spends 3-4 months a year there at the bench helping to develop novel techniques to investigate in situ mitochondrial bioenergetics. For the rest of the year he is based in Lund, Sweden and travels extensively in Europe lecturing and teaching.
Dr. Nicholls received his Ph.D., in Biochemistry from the University of Bristol, England. He is a Fellow of the Royal Society of Edinburgh and holder of the 2008 Mitchell Memorial Medal from the European Bioenergetics Congress.