Additional Facilities & Services
At the Buck we also have a number of state-of-the-art resources available for a fee to BIRC tenants, including a leading stem cell facility and vivarium, as well as core services with expertise in bioinformatics, genomics, imaging, proteomics and metabolomics.
World Leading Stem Cell Facility
A company invested in stem cell research could not find a better home than Buck’s Regenerative Medicine Research Center (RMRC). Current tenants include Cellular Dynamics Inc., a leading developer of stem cell technologies and stem cell banking founded in 2004 by Dr. James Thomson, a pioneer in human embryonic stem cell research. The RMRC houses leading stem cell technology and scientific expertize available to BIRC tenants. Vivarium The Buck Institute
is an 11,000 sq.ft. AAALAC-accredited facility for rats and mice. Vivarium staff are skilled in common technical procedures such as handling and restraint, tattooing, blood collection, oral dosing, colony management, injections and euthanasia. Core equipment includes behavioral apparatus, CT scanner, ultrasound & metabolic cages.
At the Buck we have in-house bioinformatics expertise in analysis of high-throughput data from large datasets such as next-generation sequencing, proteomics and whole genome sequencing. This Core can also build databases, mobile apps and websites on demand. More information on the Bioinformatics Core.
The Buck Genomics Core has considerable experience with genome-wide expression analyses, from microarrays and RNASeq (“NextGen sequencing”) to high-throughput qPCR using the latest technology. A robust analytical workflow facilitates processing of a broad range of species, tissues and cell types, including single cell analyses.
Morphology & Imaging Core
The Morphology and Imaging Core (MIC) services range from hiring of equipment, to training and/or direct participation by Core members. MIC customizes and optimizes protocols for histology, cytochemistry, immunostaining, functional imaging and image analysis methodologies, using brightfield, DIC, fluorescence, laser confocal, or transmission electron microscopy and state-of-the-art software to analyze and quantify data in up to 4D. More information on the Morphology & Imaging Core.
The Proteomics Core innovates, develops and implements advanced protein analytical technologies (including quantitative proteomics, posttranslational modifications, protein dynamics and biomarker discovery) to advance basic biology and biomedical research.
Buck’s Metabolomics Core has the capability to measure a diverse array of small molecules and peptides from a variety of model systems, including cultured cells and mouse tissue.
*More information on any core facilities available on request